Italian Sub Grilled Cheese Sandwich

The Italian Sub Grilled Cheese is a savory, melty masterpiece that combines the classic flavors of an Italian grinder with the comfort of a perfectly toasted sandwich. Featuring a layers of salami, pepperoni, and provolone, it is brought to life with a signature tangy lettuce topping that offers a refreshing crunch in every bite. This dish is an easy, 20-minute solution for those craving a hearty, deli-style experience at home.

Pin it

What makes this sandwich stand out is the preparation of the bread and the zesty dressing. Using sturdy Italian bread ensures the sandwich holds up to the hearty fillings, while the blend of red wine vinegar and dried oregano provides that unmistakable Italian deli aroma. Every bite is a balance of golden-brown crispness and melty, savory goodness.

Ingredients

• Bread & Dairy: 4 slices Italian bread or sturdy white sandwich bread, 2 tablespoons softened unsalted butter, 4 slices provolone cheese
• Meats: 6 slices salami, 6 slices pepperoni
• Lettuce Topping: 1 cup shredded iceberg lettuce, 2 tablespoons mayonnaise, 1 tablespoon red wine vinegar, 1 teaspoon dried oregano, salt and freshly ground black pepper to taste
• Optional Additions: 2 tablespoons mild pepperoncini rings (drained), 2 tablespoons thinly sliced red onion

Instructions

Step 1

In a bowl, combine shredded lettuce, mayonnaise, red wine vinegar, oregano, salt, and pepper. Mix well. Set aside.

Step 2

Lay out the bread slices and spread one side of each with softened butter.

Step 3

Place two slices, buttered side down, on a work surface. Top each with 2 slices provolone, 3 slices salami, and 3 slices pepperoni.

Step 4

Add optional pepperoncini and red onion if desired.

Step 5

Spread the lettuce mixture evenly over the meats and cheese.

Step 6

Top each sandwich with the remaining bread slices, buttered side up.

Step 7

Heat a large skillet or grill pan over medium heat. Place sandwiches in the pan and cook 3–4 minutes per side, pressing gently, until bread is golden and cheese is melted.

Step 8

Remove from heat, slice in half, and serve hot.

Zusatztipps für die Zubereitung

Using a skillet or grill pan over medium heat ensures the bread toasts evenly without burning before the provolone is fully melted. Pressing the sandwich gently with a spatula during the cooking process helps the ingredients meld together for a better bite.

Varianten und Anpassungen

Feel free to substitute the Italian bread with whole wheat or sourdough for a different flavor profile. For those who enjoy a spicier kick, add hot giardiniera or extra pepperoncini rings to the meat layer before grilling.

Serviervorschläge

This Italian Sub Grilled Cheese pairs perfectly with a side of kettle chips for maximum crunch or a simple tomato salad to add a fresh, acidic contrast to the rich meats and cheeses.

Pin it

Packed with 24g of protein per serving and exploding with classic Italian flavors, this sandwich is a satisfying meal for any occasion. Whether you're looking for an upgraded lunch or a fun twist on dinner, the combination of warm meats and tangy lettuce makes this recipe an instant favorite.

Recipe FAQ

→ Can I use different bread types?

Yes, Italian bread works best for authenticity, but you can substitute with sourdough, whole wheat, or ciabatta for different textures and flavors.

→ How do I prevent the bread from getting too crispy?

Cook over medium heat rather than high heat, and reduce cooking time to 2-3 minutes per side. Monitor the color carefully to achieve golden brown without burning.

→ What makes the cheese melt evenly?

Press gently on the sandwich while grilling and keep the heat at medium. Covering the pan briefly with a lid traps steam and accelerates melting.

→ Can I prepare this ahead of time?

Assemble the lettuce mixture in advance and store in the refrigerator. Build sandwiches just before grilling for optimal bread texture and cheese quality.

→ What are good side pairings?

Serve with kettle chips, a fresh tomato salad, or Italian pickles. A cold beverage like iced tea or lemonade complements the rich, savory flavors perfectly.

→ How spicy will this sandwich be?

It's mild by default with just oregano. Add pepperoncini or hot giardiniera for a spicy kick, adjusting heat level based on your preference.